Esophageal Cancer

DESCRIPTION AND TYPES

 

Esophageal cancer occurs in the tube that carries food from the mouth to the stomach. Although survival rates have improved over the years, esophageal cancer is usually diagnosed when it has advanced and is more difficult to treat.

 

Types of Esophageal Cancer

Squamous cell carcinoma occurs in the cells lining the esophagus. This type of esophageal cancer is more common in black people.

Adenocarcinoma occurs in glandular tissue, most often in the lower part of the esophagus near the stomach. It is the most common type of esophageal cancer. Adenocarcinomas are more common among Caucasians.

Esophageal Cancer Symptoms

Esophageal cancer symptoms of  are often not evident during its early stages. Even though symptoms may not mean cancer, people should consider contacting a doctor when experiencing the following symptoms:

  • Difficulty swallowing (dysphagia)
  • Pain, pressure or burning in the throat or chest
  • Weight loss
  • Vomiting
  • Hoarseness
  • Persistent hiccups
  • Chronic cough

...AND MD ANDERSON

PREVENTION

 

Risk Factors

  • Long-term history of smoking
  • Consumption of alcohol, especially when combined with smoking
  • Barrett's Esophagus: a condition in which chronic acid reflux causes changes in the cells lining the lower esophagus, increasing the risk of adenocarcinoma
  • Achalasia: a disease in which the esophagus fails to move food into the stomach properly
  • Tylosis: a rare, inherited disorder that causes excess skin to grow on the soles of the feet and palms and has a near 100% chance of developing into esophageal cancer
  • Esophageal webs: flaps of tissue that protrude into the esophagus, making swallowing difficult 
  • Lye or other caustic substances: when ingested, such substances can cause scarring that may progress to cancer years later

DIAGNOSIS

 

Diagnosing esophageal cancer can be done in various ways, including:

X-rays of the gastrointestinal tract.

Esophagoscopy: a thin tube is inserted into the mouth to examine the inside of the esophagus. This procedure can also be used to collect cell samples from the stomach for analysis.

CT scans are used after a positive diagnosis to determine the extent, or spread of the cancer.

TREAT

 

Treatment for esophageal cancer depends on the stage.

Surgery is the most common treatment for esophageal cancer. There are two surgical techniques:

Esophagectomy: The cancerous portions of the esophagus and neighboring lymph nodes are removed.

Radical esophagectomy: The entire esophagus and the top portion of the stomach are removed.

Chemotherapy, the use of drugs to kill cancer cells, is most often combined with radiation therapy.

Photodynamic therapy: laser-sensitive chemicals are injected into the tumor site. A laser beam then targets the chemicals to destroy the tumor.

Events

21-22 June 2012

Goals

The program is designed to cover the pathobiology of a wide spectrum of neoplastic disorders with emphasis on innovative diagnostic tools. The conference will focus on molecular mechanism for malignant transformation and classification of neoplasms, with particular emphasis...